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Are Steroids Colourful to Health? Articles Database Articles by Writer Articles by Hassan Hanif Madni Are Steroids Colourful to Health?

Are Steroids Colourful to Health?

Hassan Hanif Madni

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Some days back when I was bulking up, An old friend of mine came to my home and saw me. He was just surprised that I have become so much fat, He didnt knew that I was bulking at that time. I said ya I have become fat so he told me to use steroids. I asked him about and he told me that the use of CLENBUTEROL and PROVIRON using combinely results in fat loss. And he further told that he has been using it too and he had lost 10 Kgs just in a month. But if we think from our mind that 10 KGS ???.. Its a big achievement but is using steroids safe ???....

The question raised in my mind again and again. SO I planned to research about it and I got a lot of information and facts to share with you.


What are Steroids?
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Steroids are a class of hormones synthesized from cholesterol. All steroids share the same basic four-ring carbon structure, but differ in the number of carbon atoms attached to the number 17 carbon atom in the structure, and in the manner in which hydrogen (H), oxygen (O), and the hydroxyl (OH) groups are attached to the carbon atoms. There are various types of steroids. For example, corticosteroids, such as predispose or cortisone, are anti-inflammatory, catabolic compounds that break tissue down. They are completely different from the substances known as anabolic steroids. The term "anabolic steroids" commonly refers to steroids which are synthetically produced, molecularly altered derivatives (or "analogs") of testosterone. Naturally occurring testosterone is the primary sex hormone found in men, produced primarily by the Leydig cells of the testes. The adrenal glands are the primary source of testosterone in women, where testosterone is produced in a much lesser (10 to 15 times lesser) amount.

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The History of Steroids
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Steroids was developed in the 1940s in Germany and used experimentally on their troops during World War II, the drugs ability to stimulate tissue growth and protein synthesis lead them to believe that the drug might be beneficial to treat burn victims and towards other war accidents. The drug was never such a big success, because other drugs with fewer side effects were discovered, and the legal use of steroids still seems to be declining.

The Legal Use of Steroids
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Steroids are used for treating anemia, because of it's ability to increase the production of red blood corpuscles (red blood cells). They are also used for treatment of leukemia, cancer mammae, and at times steroids are also used for general strengthening therapy. Steroids have also been tried in combination with other drugs as a means of helping AIDS patients.

Why Use Steroids?
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Enhanced recuperation / Reduced recovery time Strength increases Reduced body fat Enlarged muscle size Many of these effects are only temporary, which means that once you get off steroids most of the gains disappear. As mentioned before steroids causes water retention, so steroid users will gain mass very quickly, but most of it will be water not muscles.

This will put the body through a lot of stress, loosing and gaining weight in cycles. The more positive sides of steroids are that they seem to be able to suppress the body's production of the stress hormone cortisol after exercise. Cortisol is actually a muscle tissue destroyer, so by keeping the levels of cortisol down reduces muscle damage and allows for faster recuperation. So the steroid user might be able to train more frequent.

Another major effect of steroids is the increased stimulation of the protein synthesis by increasing the amount of nitrogen in the body, more protein available to the body means that the environment for muscle production is better.

A lot of steroid users report that the steroids help them lower their body fat levels, the reason for this is not clear, but some feel it is because of an increased metabolic rate. Others claim that oxidation of fat is increased because the steroids promote mitochondria growth in the cells.

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Types of Anabolic Steroids
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Some steroids were designed to be taken orally, and usually have short half-lives, generally on the order of several hours. Other variations were developed for parenteral administration (by intramuscularly injection, commonly in the buttocks), and tend to have longer half-lives than orals, usually around one to three days.

Anabolic steroids were also chemically modified to prevent rapid breakdown by the liver and thereby enable better utilization. Orally ingested compounds are absorbed from the gastrointestinal tract and must first pass through the liver before entering the blood to be distributed throughout the body. Accordingly, many oral anabolic steroids were modified by the addition of a side chain or group of molecules at the alpha position of the number 17 carbon atom through a process called alkylation's in order to withstand inactivation on this first pass. The modification of these C-17 alkylated steroids to survive liver degradation makes them unusually harsh upon the liver.

Inject able steroids are slowly absorbed into the blood stream without a first pass through the liver. Consequently, the liver experiences a much lower concentration than with oral anabolic. For this reason, most inject able steroids have little effect upon liver function. [However, a few C-17 alkylated steroids that are usually used orally in humans are available as inject able veterinary compounds (examples are stanozolol and methandrostenelone), and these have similar hepatic profiles to their oral counterparts.] Most inject able steroids undergo a process called etherification to slow quick breakdown by the liver. Most of the common inject able androgens are oil-based preparations containing a mixture of sesame seed oil and alcohol. Enhanced forms of inject able testosterone are often collectively referred to as testosterone esters. A few inject able steroids are not oil-based, but shorter-lasting, water-based suspensions (examples are the testosterone and stanozolol suspensions).

Oral VS. Injectable Steroids
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Injectable steroids are longer lasting in the body, but therefore they can be detected in your body for a longer period of time, so athletes that are likely to be doping tested have shifted from using injectables to orals.

The problem with orals however, aside from the fact that they are not as long lasting, is that they put a lot of strain on the liver as they must be processed there. Larger quantities are also needed as a lot of it is broken down before it enters the bloodstream.

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Anabolic Steroid Use by Women and Teenagers
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Without question, there are health risks involved in the self-administration of any prescription medicine, particularly in the absence of a physician's advice with respect to dosages and duration of use. Further, without regular monitoring by a doctor, some side effects may go unnoticed or untreated until it is too late. Anabolic steroids can have adverse effects upon the body, and the risks for teenagers and women are higher than for adult males. Since large exogenous doses of androgens are more foreign to a woman's body than to a man's, their effect on the delicate hormonal balance of a woman is more profound. Excessive growth of body hair (hirsutism), coarsening of the skin, male pattern baldness, and deepening of the voice may occur (especially at massive dosages) and are generally not reversible upon discontinuance of steroids. Other possible effects particular to women include heavy facial masculinization, breast tissue reduction, alterations in menstrual cycles, and clitoral enlargement. Legal issues aside, any woman considering the use of high-dose androgens for physical enhancement must seriously weigh the perceived benefits against the quite unappealing potential cosmetic costs.

For teenagers, there is the additional risk of premature closure of the growth plates of the long bones. Even if not for this added risk, the self-administration of anabolic by teenagers must be strongly discouraged. As compared to mature adults, teenagers are much more likely to abuse anabolic steroids to the possible detriment of their health. Generally less focused upon long-range health than adults, more susceptible to peer pressure, and eager for fast results, teenagers are more likely to use anabolic in dangerously high dosages and without any medical supervision. Also, as it is recognized that the effects of anabolic upon size and strength are partially (and sometimes even completely) temporary, teens seem particularly less willing to suffer these post-cycle size and strength reductions, and are more likely to continuously use high-dose steroids for prolonged periods. Even Dan Duchaine, author of the Underground Steroid Handbook II (1989) and a favorite target of the proponents of steroid criminalization, is opposed to steroid use by teenagers. Clearly, even in countries where steroids can be legally obtained without a prescription, it is this writer's opinion that the choice to use them for physical enhancement should be made by mature, informed adults with a pre-established dedication to serious weight-training for several years. Anabolic steroids should never be used by beginning lifters, those with dubious commitments to weight-training, or those simply seeking a substitute for hard work. Parents with suspicions or concerns about their teen children experimenting with anabolic should see Wright & Cowart (1990), Chapter 4, "Recognizing Anabolic Steroid Use in Adolescents," pp. 71 -91. [But as strongly as the juvenile use of anabolic should be discouraged, there is a major question as to whether our nation's present "criminalization" approach is working. See, Do Our Anabolic Steroid Laws Work? section.]

Adverse Effects of Excess Androgens
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The average adult male production of testosterone is less than 10 milligrams (mg) per day. Supplemental androgens can raise blood androgen levels to many times the amount that could be naturally produced. All these extra androgens will effect the body's hormonal balance, including the reproductive system. Because anabolic mimic endogenous androgens (i.e., your own natural testosterone) in the negative feedback loop of the hypothalamic-pituitary-gonadal axis, they cause the body to decrease its own production. Exactly how long it takes for the body to begin to shut down its own production of androgens is uncertain, although some have estimated it at about three weeks of steroid therapy. This induced hypogonadal state is characterized by decreased serum testosterone levels, associated testicular atrophy, and impaired sperm production that results in temporary infertility. It is this aspect of anabolic therapy that has been the focus of numerous studies testing the use of anabolic as a form of male contraception. But it is important to note that these effects are reversible with discontinuance of the steroids (Haupt and Rover, 1984, p. 481), and that no case of permanent sterility as a result of prolonged high-dose steroid consumption has ever been reliably documented (Yesalis and Cowart, 1998, p. 53).

Steroid use can also effect the libido. It is common for the sex drive to heighten during a cycle but decrease toward the end and after because the body's own production of testosterone has been temporarily shut down due to the exogenous steroids. Decreased testicular size is also not uncommon with prolonged usage. Both of these adverse effects are reversible upon the body's own recuperation and often can be avoided altogether with the administration of gonadotropin stimulating drugs, which "jump-start" the body's natural production of testosterone (Phillips, 1991, p. 131; Di Pasquale, 1990, pp. 24-26).

Anabolic Steroids and the Liver
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Anabolic steroids are processed by the liver. As discussed earlier, C-17 alkylated oral steroids (steroids with an alkyl group added at the alpha position of the "C-17" or number 17 carbon atom of the molecule to withstand total degradation on their first pass through the liver [see Steroids 101 section above]) are unusually harsh on the liver. For this reason, even moderate short-term administration of these C-17 oral steroids can effect liver function test readings. Elevated liver counts indicating liver stress (toxicity) have been reported in recent studies of somewhat moderate oral anabolic steroid therapy (daily doses of 40 and 80 mg of oxandrolone [Oxandrin, formerly Anavar]) as reported in the online periodical Metabolic, edited by Michael Mooney ( However, these elevated liver function readings will return to normal after cessation of a moderate, short-term steroid cycle. I could find not one case to the contrary. Further, it is recognized that intense weight training alone often causes changes in liver function tests, including SGOT, SGPT and LDH (this is something that all physicians monitoring athletes using anabolic should be familiar with).

Anabolic Steroids and the Heart
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How cardiac risk might be increased by the use of steroids is a subject of speculation and some controversy. High blood pressure is perhaps "one of the most exaggerated claims" of steroid-related health risks, and remains unconfirmed despite numerous studies (Friedl, 1993, pp. 119-120). Regarding blood lipid levels, oral steroids in particular seem to cause a reduction in HDL (high-density lipoprotein cholesterol) levels in some steroid users. However, changes in the blood lipid levels now appear to begin to recover within about a month after discontinued use, and, in fact, most studies do not report an increase in total cholesterol (Yesalis & Cowart, p. 54).

Hassan Hanif Madni

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Hassan Hanif Madni

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